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Mouse Ddx3y ORF Clone(NM_012008.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR251399

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Product Information

Gene Information

Cat. No. CDCR251399
Product Type ORF Clone
Gene Abbr Ddx3y
Species Mouse
Tag C-terminal TurboGFP
ORF Size 1976 bp
Size 10 ug
Vector pCMV6-AC-GFP
Target Gene DDX3Y
Background The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
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