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Mouse Dact1 cDNA Clone(NM_001190466.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG021457

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Gene Information

Cat. No. CDFG021457
Product Type cDNA clone
Gene Abbr Dact1
Species Mouse
ORF Size 2448bp
Size 10 ug
Vector pCMV6Entry
Target Gene DACT1
Background The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
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