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Mouse Col4a6 cDNA Clone(NM_053185.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL002953

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Gene Information

Cat. No. CDFL002953
Product Type cDNA clone
Gene Abbr Col4a6
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene COL4A6
Background This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
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