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Mouse Cntfr ORF clone (NM_001146080.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR048960

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Gene Information

Cat. No. CDCR048960
Description Mus musculus ciliary neurotrophic factor receptor (Cntfr), transcript variant 3, mRNA.
Product Type ORF clone
Gene Abbr Cntfr
Species Mouse
ORF Size 342
Format purified plasmid
Vector pDONR
Target Gene CNTFR
Background This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
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