Mouse CHMP3 ORF clone(NM_025783.3)

Name: Mouse CHMP3 ORF clone(NM_025783.3)
SKU: CDCR007560
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR007560

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Product Information

Gene Information

Cat. No.	CDCR007560
Product Type	ORF clone
Gene Abbr	CHMP3
Species	Mouse
Host Cell	Bacterial: Spectinomycin
Source	Bacterial: Spectinomycin
ORF Size	2592bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mChmp3 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

CHMP3

Background

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]

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