Human ZEB1 adenoviral particles

Name: Human ZEB1 adenoviral particles
SKU: AD18020Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD18020Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD18020Z
Description	Adenovirus with ORF of zinc finger E-box binding homeobox 1 (ZEB1), transcript variant 6.
Gene	ZEB1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens ]
Gene Symbol	ZEB1
Synonyms	ZEB1; zinc finger E-box binding homeobox 1; posterior polymorphous corneal dystrophy 3 , PPCD3, TCF8, transcription factor 8 (represses interleukin 2 expression); zinc finger E-box-binding homeobox 1; AREB6; BZP; NIL 2 A; ZEB; Zfhep; Zfhx1a; negative regulator of IL2; delta-crystallin enhancer binding factor 1; posterior polymorphous corneal dystrophy 3; zinc finger homeodomain enhancer-binding protein; transcription factor 8 (represses interleukin 2 expression); TCF8; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1; MGC133261;
GeneID	6935
Uni ProtID	P37275
mRNA Refseq	BC112392
Chromosome Location	10p11.22
Function	E-box binding; E-box binding; chromatin binding; double-stranded DNA binding; metal ion binding; protein binding; sequence-speci
Pathway	Hypertrophy Model, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
MIM	189909

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