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Human UCMA cDNA Clone(NM_145314.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG009015

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Product Information

Gene Information

Cat. No. CDFG009015
Product Type cDNA clone
Gene Abbr UCMA
Species Human
ORF Size 840bp
Size 10 ug
Vector pCMV6-XL5
Target Gene UCMA
Background This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
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