Human TDG Knockdown Cell Line - Glioma

Name: Human TDG Knockdown Cell Line - Glioma
SKU: CSC-RK0228
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0228

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0228
Description	This cell line is engineered to stably express shRNA targeting human TDG.
Target Gene	TDG
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TDG thymine-DNA glycosylase [ Homo sapiens ]
Gene Symbol	TDG
Synonyms	TDG; thymine-DNA glycosylase; G/T mismatch-specific thymine DNA glycosylase; EC 3.2.2.29
GeneID	6996
Uni ProtID	Q13569
mRNA Refseq	BC037557
Chromosome Location	12q24.1
Function	damaged DNA binding; mismatched DNA binding; protein binding; pyrimidine-specific mismatch base pair DNA N-glycosylase activity
Pathway	Base excision repair, conserved biosystem; Depyrimidination, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosyst
MIM	601423

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