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Human SMUG1 Knockdown Cell Line-LN428 Glioma

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Cat.No.
CSC-RK0219
Background
This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
LN428 glioma
Ship
Dry ice
Gene Information
Official Symbol
SMUG1
Synonyms
SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1; single-strand selective monofunctional uracil DNA glycosylase; FDG; HMUDG; UNG3; MGC104370;
Gene ID
MIM
UniProt ID
Q53HV7
Chromosome Location
12q13.11-q13.3
Pathway
Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged pyrimidine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function
DNA N-glycosylase activity; DNA binding; hydrolase activity, acting on glycosyl bonds; protein binding; single-strand selective uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity;

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