Human SLC19A2 adenoviral particles

Name: Human SLC19A2 adenoviral particles
SKU: AD14787Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD14787Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD14787Z
Description	Adenovirus with ORF of solute carrier family 19 (thiamine transporter), member 2 (SLC19A2).
Gene	SLC19A2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	SLC19A2 solute carrier family 19 (thiamine transporter), member 2 [ Homo sapiens ]
Gene Symbol	SLC19A2
Synonyms	SLC19A2; solute carrier family 19 (thiamine transporter), member 2; TRMA; thiamine transporter 1; THTR1; thTr-1; solute carrier family 19 member 2; high affinity thiamine transporter; reduced folate carrier protein (RFC) like; TC1; THT1; THMD1;
GeneID	10560
Uni ProtID	O60779
mRNA Refseq	BC018514
Chromosome Location	1q23.3
Function	folic acid binding; folic acid transporter activity; reduced folate carrier activity; thiamine transmembrane transporter activity; thiamine uptake transmembrane transporter activity;
Pathway	Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Vitamin B1 (thiamin) metabolism, organism-specific biosystem; Vitamin digestion and absorption, organism-specific biosystem; Vitamin digestion and absorption, conserved biosystem;
MIM	603941

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