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Human SHC3 adenoviral particles

For research use only. Not intended for any clinical use.

Cat. No. :   AD14628Z

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. AD14628Z
Description Adenovirus with ORF of SHC (Src homology 2 domain containing) transforming protein 3 (SHC3).
Gene SHC3
Species Human
Titer Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.
Gene Name SHC3 SHC (Src homology 2 domain containing) transforming protein 3 [ Homo sapiens ]
Gene Symbol SHC3
Synonyms SHC3; SHC (Src homology 2 domain containing) transforming protein 3; src homology 2 domain containing transforming protein C3; SHC-transforming protein 3; N Shc; NSHC; SHCC; protein Rai; neuronal Shc; SH2 domain protein C3; SHC-transforming protein C; src homology 2 domain-containing transforming protein C3; src homology 2 domain-containing-transforming protein C3; RAI; N-Shc; FLJ45325; DKFZp686H1544;
Gene ID 53358
Uni Prot ID Q92529
m RNA Refseq BC026314
Chromosome Location 9q22.1
Function protein binding; signal transducer activity;
Pathway Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; ErbB signaling pathway, organism-specific biosystem;
MIM 605263
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