Human SH3RF2 adenoviral particles

Name: Human SH3RF2 adenoviral particles
SKU: AD14615Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD14615Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD14615Z
Description	Adenovirus with ORF of SH3 domain containing ring finger 2 (SH3RF2).
Gene	SH3RF2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	SH3RF2 SH3 domain containing ring finger 2 [ Homo sapiens ]
Gene Symbol	SH3RF2
Synonyms	SH3RF2; SH3 domain containing ring finger 2; PPP1R39, protein phosphatase 1, regulatory subunit 39; putative E3 ubiquitin-protein ligase SH3RF2; FLJ23654; heart protein phosphatase 1 binding protein; Hepp1; POSH eliminating RING protein; POSHER; RNF158; RING finger protein 158; POSH-eliminating RING protein; SH3 domain-containing RING finger protein 2; heart protein phosphatase 1-binding protein; protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; HEPP1; PPP1R39; MGC90410; MGC149788; MGC149789;
Gene ID	153769
Uni Prot ID	Q8TEC5
m RNA Refseq	BC073914
Chromosome Location	5q32
Function	ligase activity; metal ion binding; phosphatase binding; protein binding; protein phosphatase 1 binding; protein phosphatase inhibitor activity; zinc ion binding;
MIM	613377

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