Human RNF40 adenoviral particles

Name: Human RNF40 adenoviral particles
SKU: AD13894Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD13894Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD13894Z
Description	Adenovirus with ORF of ring finger protein 40 (RNF40), transcript variant 3.
Gene	RNF40
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	RNF40 ring finger protein 40, E3 ubiquitin protein ligase [ Homo sapiens ]
Gene Symbol	RNF40
Synonyms	RNF40; ring finger protein 40, E3 ubiquitin protein ligase; ring finger protein 40; E3 ubiquitin-protein ligase BRE1B; BRE1 E3 ubiquitin ligase homolog B (S. cerevisiae); BRE1B; KIAA0661; RBP95; STARING; BRE1-B; Rb-associated protein; BRE1 E3 ubiquitin ligase homolog B; 95 kDa retinoblastoma-associated protein; 95 kDa retinoblastoma protein binding protein; MGC13051; DKFZp686K191;
Gene ID	9810
Uni Prot ID	O75150
m RNA Refseq	BC006133
Chromosome Location	16p11.2-p11.1
Function	ligase activity; metal ion binding; protein binding; protein complex binding; protein homodimerization activity; syntaxin-1 binding; ubiquitin protein ligase binding; contributes_to ubiquitin-protein ligase activity; zinc ion binding;
MIM	607700

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