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Human RAD21 Knockdown Cell Line-LN428 Glioma

Cat.No.
CSC-RK0248
Abbr
LN428 Glioma-HuRAD21 Knockdown
Alias
RAD21,hHR21,KIAA0078,SCC1,NXP-1,HR21,MCD1,NXP1,HRAD21,FLJ25655,FLJ40596,
Growth Properties
Adherent
Host Cell
LN428 glioma
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

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