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RAD21

Official Full Name
RAD21 cohesin complex component
Organism
Homo sapiens
GeneID
5885
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]
Synonyms
MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21;

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