Human Pla2g4a adenoviral particles

Name: Human Pla2g4a adenoviral particles
SKU: AD12360Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD12360Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD12360Z
Description	Adenovirus with ORF of phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A).
Gene	Pla2g4a
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) [ Homo sapiens ]
Gene Symbol	PLA2G4A
Synonyms	PLA2G4; cPLA2-alpha
Gene Description	phospholipase A2, group IVA (cytosolic, calcium-dependent)
GeneID	5321
Uni ProtID	P47712
mRNA Refseq	NM_024420.2
Protein Refseq	NP_077734.1
Chromosome Location	1q25
Function	calcium ion binding; calcium-dependent phospholipase A2 activity; calcium-dependent phospholipid binding; hydrolase activity; lysophospholipase activity; phospholipase A2 activity; phospholipase A2 activity; phospholipase A2 activity;
Pathway	ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Acyl chain remodeling of CL, organism-specific biosystem; Acyl chain remodelling of PC, organism-specific biosystem; Acyl chain remodelling of PE, organism-specific biosystem; Acyl chain remodelling of PG, organism-specific biosystem; Acyl chain remodelling of PI, organism-specific biosystem; Acyl chain remodelling of PS, organism-specific biosystem;
MIM	600522

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