Human PRDX1 Knockdown Cell Line-HeLa

Name: Human PRDX1 Knockdown Cell Line-HeLa
SKU: CSC-RK0283
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0283

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0283
Background	This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.
Target Gene	PRDX1
Abbr	HeLa-HuPRDX1 Knockdown
Alias	PRDX1, PAGA, NKEFA, NKEF-A, PAG, PAGB, PRX1, PRXI, MSP23, TDPX2
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PRDX1 peroxiredoxin 1 [ Homo sapiens ]
Gene Symbol	PRDX1
Synonyms	PRDX1; peroxiredoxin 1; PAGA; peroxiredoxin-1; NKEFA; NKEF-A; thioredoxin peroxidase 2; proliferation-associated gene A; natural killer-enhancing factor A; proliferation-associated gene protein; natural killer cell-enhancing factor A; thioredoxin-dependent peroxide reductase 2; PAG; PAGB; PRX1; PRXI; MSP23; TDPX2;
GeneID	5052
Uni ProtID	Q06830
mRNA Refseq	BC007063
Chromosome Location	1p34.1
Function	oxidoreductase activity; peroxidase activity; protein binding; thioredoxin peroxidase activity;
Pathway	Coregulation of Androgen receptor activity, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; Selenium Pathway, organism-specific biosystem;
MIM	176763

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