Human PPP1CC adenoviral particles

The PPP1CC gene encodes protein phosphatase 1 catalytic subunit γ (PP1γ), which belongs to the serine/threonine phosphatase family. PP1 plays a key role in a variety of cellular processes, including cell cycle progression, glycogen metabolism, apoptosis, and neuronal signaling. PPP1CC isoforms, particularly PP1γ, are highly conserved and widely expressed in tissues, especially in the testis and brain. It modulates key signaling pathways by dephosphorylating target proteins, thereby regulating their activity. PPP1CC dysregulation has been implicated in diseases such as cancer, neurodegenerative diseases, and male infertility.

Human PPP1CC Adenoviral Particles are genetically engineered viral vectors designed to deliver the PPP1CC gene to mammalian cells for functional studies or therapeutic applications. These particles are based on a replication-defective adenovirus, which ensures efficient transduction of a variety of cell types, including dividing and non-dividing cells. This adenoviral system has high transduction efficiency and stable transgene expression, making it an ideal tool for overexpressing PPP1CC in vitro or in vivo. These particles can be used to study the role of PP1γ in cell signaling, disease mechanisms, or potential gene therapy approaches.