Human NUP214 adenoviral particles

Name: Human NUP214 adenoviral particles
SKU: AD11123Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD11123Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD11123Z
Description	Adenovirus with ORF of nucleoporin 214kDa (NUP214).
Gene	NUP214
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	NUP214 nucleoporin 214kDa [ Homo sapiens ]
Gene Symbol	NUP214
Synonyms	CAN; CAIN; N214; D9S46E
Gene Description	nucleoporin 214kDa
GeneID	8021
Uni ProtID	P35658
mRNA Refseq	NM_005085.2
Protein Refseq	NP_005076.3
Chromosome Location	9q34.1
Function	nucleocytoplasmic transporter activity; protein binding; transporter activity;
Pathway	Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Disease, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; Export of Viral Ribonucleoproteins from Nucleus, organism-specific biosystem;
MIM	114350

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