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Human NF-kB Prom/Luciferase/Hyg Reporter Stable Cell Line-Hela

Cat.No.
CSC-RR0020
Human NF-kB Prom/Luciferase/Hyg Reporter Stable Cell Line-Hela
Abbr
Hela-HuNF-kB Prom/Luciferase/Hyg
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
NFkB plays an important role in controlling biological processes including immune and inflammatory responses, developmental processes, cellular growth, and apoptosis. In response to various stimuli, such as stress, cytokines, free radicals, ultraviolet irradiation, and bacterial or viral antigens, NFkB is activated and translocated from cytokine to the nucleus, where NFkB binds to its response element on the promoter region and regulates a wide spectrum of gene expression. Dysfunction of NFkB activity is associated with cancer, inflammatory and autoimmune disease, and viral infection. Monitoring the NFkB activity is essential to unveil the mechanism of these diseases and conduct drug discovery.

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