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Human NEIL2 Knockdown Cell Line-LN428 Glioma

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Cat.No.
CSC-RK0216
Background
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
LN428 glioma
Ship
Dry ice
Gene Information
Official Symbol
NEIL2
Synonyms
NEIL2; nei endonuclease VIII-like 2 (E. coli); nei like 2 (E. coli); endonuclease 8-like 2; FLJ31644; MGC2832; MGC4505; NEH2; nei like 2; nei homolog 2; nei-like protein 2; endonuclease VIII-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; NEI2;
Gene ID
MIM
UniProt ID
Q969S2
Chromosome Location
8p23.1
Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
Function
DNA-(apurinic or apyrimidinic site) lyase activity; damaged DNA binding; hydrolase activity, hydrolyzing N-glycosyl compounds; lyase activity; metal ion binding; zinc ion binding;

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