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NEIL2


Official Full Name
nei like DNA glycosylase 2
Organism
Homo sapiens
Gene ID
252969
Background
This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. [provided by RefSeq, Mar 2017]
Synonyms
NEH2; NEI2

Cat.No. Product Name Price
SHH351172 shRNA set against Human NEIL2 (NM_145043.2) Inquiry
SHH351176 shRNA set against Mouse NEIL2 (NM_201610.2) Inquiry
SHH351180 shRNA set against Rat NEIL2 (NM_001107270.1) Inquiry
SHW004128 shRNA set against Chicken NEIL2 (NM_001277833) Inquiry
Cat.No. Product Name Price
CDFH012392 Human NEIL2 cDNA Clone(NM_001135746.1) Inquiry
MiUTR1H-06716 NEIL2 miRNA 3'UTR clone Inquiry
MiUTR1H-06715 NEIL2 miRNA 3'UTR clone Inquiry
MiUTR1H-06714 NEIL2 miRNA 3'UTR clone Inquiry
CDFR006993 Rat Neil2 cDNA Clone(NM_001107270.1) Inquiry
CDFL008276 Mouse Neil2 cDNA Clone(NM_201610.2) Inquiry
CDFH012394 Human NEIL2 cDNA Clone(NM_001135747.1) Inquiry
CDFH012393 Human NEIL2 cDNA Clone(NM_001135748.1) Inquiry
MiUTR1H-06717 NEIL2 miRNA 3'UTR clone Inquiry
MiUTR1M-07590 NEIL2 miRNA 3'UTR clone Inquiry
CDCR373991 Rat Neil2 ORF Clone(NM_001107270.1) Inquiry
CDCR350349 Human NEIL2 ORF Clone(NM_001135746.1) Inquiry
CDCL137523 Human Neil2 ORF clone (NM_201610.2) Inquiry
CDCL137519 Human NEIL2 ORF clone (NM_001135748.1) Inquiry
CDCL137517 Human NEIL2 ORF clone (NM_001135747.1) Inquiry
CDCB182683 Rabbit NEIL2 ORF clone (XM_008248868.1) Inquiry
CDCB165603 Chicken NEIL2 ORF Clone (NM_001277833) Inquiry
CDCS408125 Human NEIL2 ORF Clone (BC013952) Inquiry
CDCB157779 Human NEIL2 ORF clone (BC013952) Inquiry
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