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Human NEIL1 Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0037
Background
This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
NEIL1
Synonyms
NEIL1; nei endonuclease VIII-like 1 (E. coli); endonuclease 8-like 1; FLJ22402; FPG1; hFPG1; NEI1; NEH1; nei homolog 1; endonuclease VIII; nei-like protein 1; endonuclease VIII-like 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1;
Gene ID
MIM
UniProt ID
Q96FI4
Chromosome Location
15q33.33
Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
Function
DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; damaged DNA binding; hydrolase activity, acting on glycosyl bonds; lyase activity; protein C-terminus binding; zinc ion binding;

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