Human MAP4K2 adenoviral particles

Name: Human MAP4K2 adenoviral particles
SKU: AD09636Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD09636Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD09636Z
Description	Adenovirus with ORF of mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2).
Gene	MAP4K2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [ Homo sapiens ]
Gene Symbol	MAP4K2
Synonyms	MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2; RAB8IP; BL44; GCK; MEKKK 2; GC kinase; MEK kinase kinase 2; germinal center kinase; Rab8 interacting protein; rab8-interacting protein; MAPK/ERK kinase kinase kinase 2; germinal centre kinase (GC kinase); B lymphocyte serine/threonine protein kinase; b lymphocyte serine/threonine-protein kinase;
Gene ID	5871
Uni Prot ID	Q12851
m RNA Refseq	BC047865
Chromosome Location	11q13.1
Function	ATP binding; ATP binding; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; small GTPase regulator activity;
Pathway	Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; TNF receptor signaling pathway, organism-specific biosystem;
MIM	603166

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