Human MAP3K13 adenoviral particles

Name: Human MAP3K13 adenoviral particles
SKU: AD09623Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD09623Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD09623Z
Description	Adenovirus with ORF of mitogen-activated protein kinase kinase kinase 13 (MAP3K13), transcript variant 1.
Gene	MAP3K13
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	MAP3K13 mitogen-activated protein kinase kinase kinase 13 [ Homo sapiens ]
Gene Symbol	MAP3K13
Synonyms	MAP3K13; mitogen-activated protein kinase kinase kinase 13; leucine zipper bearing kinase; LZK; MEKK13; mixed lineage kinase; leucine zipper-bearing kinase; MLK; MGC133196;
Gene ID	9175
Uni Prot ID	O43283
m RNA Refseq	BC111726
Chromosome Location	3q27
Function	ATP binding; MAP kinase kinase kinase activity; identical protein binding; magnesium ion binding; nucleotide binding; protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity;
Pathway	Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Signaling events mediated by VEGFR1 and VEGFR2, organism-specific biosystem;
MIM	604915

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