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Human Hnrnpa1 ORF clone (NM_001039129.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL117767

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Gene Information

Cat. No. CDCL117767
Description Mus musculus heterogeneous nuclear ribonucleoprotein A1 (Hnrnpa1), transcript variant 2, mRNA.
Product Type ORF clone
Gene Abbr Hnrnpa1
Species Mouse
ORF Size 1122bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene HNRNPA1
Background This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]
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