Human HEY1 adenoviral particles

Name: Human HEY1 adenoviral particles
SKU: AD07450Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD07450Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD07450Z
Description	Adenovirus with ORF of hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 1.
Gene	HEY1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	HEY1 hairy/enhancer-of-split related with YRPW motif 1 [ Homo sapiens ]
Gene Symbol	HEY1
Synonyms	CHF2; OAF1; HERP2; HESR1; HRT-1; BHLHb31
Gene Description	hairy/enhancer-of-split related with YRPW motif 1
GeneID	23462
Uni ProtID	Q9Y5J3
mRNA Refseq	NM_001040708.1
Protein Refseq	NP_001035798.1
Chromosome Location	8q21
Function	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; microsatellite binding; protein binding; protein binding transcription factor activity; protein dimerization activity; sequence-specific DNA binding transcription factor activity; transcription factor binding;
Pathway	Delta-Notch Signaling Pathway, organism-specific biosystem; Heart Development, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
MIM	602953

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