Human Gigyf2 ORF clone (NM_001110212.1)

Name: Human Gigyf2 ORF clone (NM_001110212.1)
SKU: CDCL111597
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL111597

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Product Information

Gene Information

Cat. No.	CDCL111597
Description	Mus musculus GRB10 interacting GYF protein 2 (Gigyf2), transcript variant 2, mRNA.
Product Type	ORF clone
Gene Abbr	Gigyf2
Species	Mouse
ORF Size	3858bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

GIGYF2

Background

This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

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