Human GRIK3 adenoviral particles

Name: Human GRIK3 adenoviral particles
SKU: AD07145Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD07145Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD07145Z
Description	Adenovirus with ORF of glutamate receptor, ionotropic, kainate 3 (GRIK3).
Gene	GRIK3
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	GRIK3 glutamate receptor, ionotropic, kainate 3 [ Homo sapiens ]
Gene Symbol	GRIK3
Synonyms	EAA5; GLR7; GLUR7; GluK3; GluR7a
Gene Description	glutamate receptor, ionotropic, kainate 3
GeneID	2899
Uni ProtID	A9Z1Z8
mRNA Refseq	NM_000831.3
Protein Refseq	NP_000822.2
Chromosome Location	1p34.3
Function	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity; extracellular-glutamate-gated ion channel activity; glutamate receptor activity; ionotropic glutamate receptor activity; ionotropic glutamate receptor activity; kainate selective glutamate receptor activity;
Pathway	Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Ionotropic activity of Kainate Receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
MIM	138243

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