Human FGFR1 HEK293 Cell Lysate

Name: Human FGFR1 HEK293 Cell Lysate
SKU: CLOE-1306
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1306 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1306
Introduction	This cell lysate over-expresses the extracellular domain of human FGFR1 isoform 4 (NP_075594.1) (Met 1-Glu 285) fused with a polyhistidine tag and the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	FGFR1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ]
Gene Symbol	FGFR1
Synonyms	CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; bFGF-R-1
Gene Description	fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
GeneID	2260
Uni ProtID	P11362
mRNA Refseq	NM_023106.2
Protein Refseq	NP_075594.1
Chromosome Location	8p12
Function	ATP binding; cell adhesion molecule binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast growth factor-activated receptor activity; glycoprotein binding; heparin binding; identical protein binding; protein binding; protein homodimerization activity; protein tyrosine kinase activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Axon guidance, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem;
MIM	136350

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