Human EIF2B2 adenoviral particles

Name: Human EIF2B2 adenoviral particles
SKU: AD05351Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD05351Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD05351Z
Description	Adenovirus with ORF of eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa (EIF2B2).
Gene	EIF2B2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa [ Homo sapiens ]
Gene Symbol	EIF2B2
Synonyms	EIF2B2; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); translation initiation factor eIF-2B subunit beta; EIF 2Bbeta; EIF2B; S20I15; S20III15; eIF-2B GDP-GTP exchange factor subunit beta; EIF-2Bbeta;
Gene ID	8892
Uni Prot ID	P49770
m RNA Refseq	BC000494
Chromosome Location	14q24.3
Function	ATP binding; GTP binding; contributes_to guanyl-nucleotide exchange factor activity; contributes_to guanyl-nucleotide exchange factor activity; protein binding; contributes_to translation
Pathway	Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Recycling of eIF2:GDP, organism-specific biosystem;
MIM	606454

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