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Human DR6 ORF clone(NM_014452.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL183959

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Gene Information

Cat. No. CDCL183959
Product Type ORF clone
Gene Abbr DR6
Species Human
ORF Size 1968bp
Vector pMD18-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene TNFRSF21
Background This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
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