Human DLG1 adenoviral particles

Name: Human DLG1 adenoviral particles
SKU: AD04900Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD04900Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD04900Z
Description	Adenovirus with ORF of discs, large homolog 1 (Drosophila) (DLG1), transcript variant 2.
Gene	DLG1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	DLG1 discs, large homolog 1 (Drosophila) [ Homo sapiens ]
Gene Symbol	DLG1
Synonyms	hdlg; DLGH1; SAP97; SAP-97; dJ1061C18.1.1
Gene ID	1739
Uni Prot ID	Q12959
m RNA Refseq	NM_001098424.1
Protein Refseq	NP_001091894.1
Chromosome Location	3q29
Function	L27 domain binding; cytoskeletal protein binding; guanylate kinase activity; ion channel binding; mitogen-activated protein kinase kinase binding; phosphatase binding; phosphoprotein phosphatase activity; potassium channel regulator activity; potassium channel regulator activity; protein C-terminus binding; protein binding; protein complex scaffold; protein kinase binding;
Pathway	Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Axon guidance, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Developmental Biology, organism-specific biosystem; E-cadherin signaling in the nascent adherens junction, organism-specific biosystem; Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, organism-specific biosystem;
MIM	601014

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