Human CYP1A2 adenoviral particles

Name: Human CYP1A2 adenoviral particles
SKU: AD04500Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD04500Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD04500Z
Description	Adenovirus with ORF of cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2).
Gene	CYP1A2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 [ Homo sapiens ]
Gene Symbol	CYP1A2
Synonyms	CP12; P3-450; P450(PA)
Gene Description	cytochrome P450, family 1, subfamily A, polypeptide 2
Gene ID	1544
Uni Prot ID	P05177
m RNA Refseq	NM_000761.3
Protein Refseq	NP_000752.2
Chromosome Location	15q24.1
Function	aromatase activity; caffeine oxidase activity; demethylase activity; electron carrier activity; enzyme binding; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;
Pathway	Aflatoxin B1 metabolism, organism-specific biosystem; Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2, organism-specific biosystem; Arylamine metabolism, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Caffeine metabolism, organism-specific biosystem; Caffeine metabolism, conserved biosystem; Chemical carcinogenesis, organism-specific biosystem;
MIM	124060

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