Human CPT1C adenoviral particles

The CPT1C gene encodes carnitine palmitoyltransferase 1C (CPT1C), a key enzyme involved in lipid metabolism, especially in regulating the oxidation of long-chain fatty acids. Unlike CPT1A and CPT1B isoforms, which are mainly expressed in liver and muscle tissue, CPT1C is mainly found in the central nervous system (CNS), especially in neurons and astrocytes. It is localized to the endoplasmic reticulum (ER) and plays a key role in metabolic sensing and energy homeostasis. CPT1C is involved in a variety of physiological processes, including appetite regulation, neuronal survival, and synaptic plasticity. Emerging studies have shown that CPT1C is associated with neurodegenerative diseases, obesity, and cancer, making it a potential therapeutic target.

Human CPT1C adenoviral particles are recombinant viral vectors designed to deliver the CPT1C gene to target cells for functional studies or therapeutic applications. These particles are based on adenovirus serotype 5 (Ad5) and have been engineered to ensure high transduction efficiency and stable gene expression in both dividing and non-dividing cells, including neurons and glial cells. The adenoviral backbone has been optimized to minimize immunogenicity while maintaining strong infectivity, making it suitable for in vitro and in vivo experiments. Human CPT1C adenoviral particles are ideal for studying the role of CPT1C in lipid metabolism, neuronal function, or disease mechanisms. These adenoviral particles are prepackaged as ready-to-use viral preparations, providing researchers with a reliable and efficient method for gene delivery, promoting advances in metabolic and neuroscience research.