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Human BMP-7 ORF clone(NM_001719.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL182889

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Gene Information

Cat. No. CDCL182889
Product Type ORF clone
Gene Abbr BMP-7
Species Human
ORF Size 1296bp
Vector pMD18-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene BMP-7
Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
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