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Human BMP-2 ORF clone(NM_001200.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL182871

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Product Information

Gene Information

Cat. No. CDCL182871
Description ORF Clone of Homo sapiens bone morphogenetic protein 2 DNA.
Product Type ORF clone
Gene Abbr BMP-2
Species Human
ORF Size 1191bp
Vector pGEM-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene BMP-2
Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
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