Transfected Stable Cell Lines
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Cat. No. : CDCL182871
| Cat. No. | CDCL182871 |
| Description | ORF Clone of Homo sapiens bone morphogenetic protein 2 DNA. |
| Product Type | ORF clone |
| Gene Abbr | BMP-2 |
| Species | Human |
| ORF Size | 1191bp |
| Vector | pGEM-T |
| Warning | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | store at -20°C |
| Target Gene | BMP-2 |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] |
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