Human BACE1(Fc) HEK293 Cell Lysate

Name: Human BACE1(Fc) HEK293 Cell Lysate
SKU: CLOE-1764
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1764 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1764
Introduction	This cell lysate over-expresses the human BACE1 (NP_036236.1) (Met 1-Thr 457) fused with the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	BACE1
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	BACE1 beta-site APP-cleaving enzyme 1 [ Homo sapiens ]
Gene Symbol	BACE1
Synonyms	BACE1; beta-site APP-cleaving enzyme 1; BACE, beta site APP cleaving enzyme; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; ASP2; BACE; HSPC104; FLJ90568; KIAA1149;
GeneID	23621
Uni ProtID	P56817
mRNA Refseq	BC065492
Chromosome Location	11q23-q24
Function	aspartic-type endopeptidase activity; beta-aspartyl-peptidase activity; enzyme binding; peptidase activity;
Pathway	Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem;
MIM	604252

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