Human Aars2 adenoviral particles

Name: Human Aars2 adenoviral particles
SKU: AD00425Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00425Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00425Z
Description	Adenovirus with ORF of alanyl-tRNA synthetase 2, mitochondrial (putative) (AARS2), nuclear gene encoding mitochondrial protein.
Gene	Aars2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	AARS2 alanyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens ]
Gene Symbol	AARS2
Synonyms	AARS2; alanyl-tRNA synthetase 2, mitochondrial (putative); AARSL, alanyl tRNA synthetase like; alanine--tRNA ligase, mitochondrial; alanine tRNA ligase 2; mitochondrial (putative); bA444E17.1; KIAA1270; alanyl-tRNA synthetase like; probable alanyl-tRNA synthetase, mitochondrial; alanine tRNA ligase 2, mitochondrial (putative); AARSL; COXPD8; MTALARS; MT-ALARS;
Gene ID	57505
Uni Prot ID	Q5JTZ9
m RNA Refseq	BC131728
Chromosome Location	6p21.1
Function	ATP binding; alanine-tRNA ligase activity; ligase activity; metal ion binding; nucleotide binding; tRNA bindi
Pathway	Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem;
MIM	612035

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