Human ATP7B adenoviral particles

Name: Human ATP7B adenoviral particles
SKU: AD01590Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD01590Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD01590Z
Description	Adenovirus with ORF of ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1.
Gene	ATP7B
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	ATP7B ATPase, Cu++ transporting, beta polypeptide [ Homo sapiens ]
Gene Symbol	ATP7B
Synonyms	ATP7B; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (Wilson disease) , WND; copper-transporting ATPase 2; Wilson disease; copper pump 2; Wilson disease-associated protein; ATPase, Cu(2+)- transporting, beta polypeptide; WD; PWD; WC1; WND;
Gene ID	540
Uni Prot ID	P35670
m RNA Refseq	BC117200
Chromosome Location	13q14.3
Function	ATP binding; copper ion binding; copper-exporting ATPase activity; copper-exporting ATPase activity; hydrolase activity; metal ion binding; nucleotide binding; protein binding;
Pathway	Ion channel transport, organism-specific biosystem; Ion transport by P-type ATPases, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
MIM	606882

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