Human AP2A2 adenoviral particles

Name: Human AP2A2 adenoviral particles
SKU: AD01131Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD01131Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD01131Z
Description	Adenovirus with ORF of adaptor-related protein complex 2, alpha 2 subunit (AP2A2), transcript variant 1.
Gene	AP2A2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	AP2A2 adaptor-related protein complex 2, alpha 2 subunit [ Homo sapiens ]
Gene Symbol	AP2A2
Synonyms	AP2A2; adaptor-related protein complex 2, alpha 2 subunit; ADTAB, CLAPA2; AP-2 complex subunit alpha-2; adaptin; alpha B; alpha adaptin C; Huntingtin interacting protein J; clathrin associated/assembly/adaptor protein; large; alpha 2; DKFZP564D1864; HIP9; HYPJ; KIAA0899; alpha2-adaptin; adaptin, alpha B; huntingtin yeast partner J; 100 kDa coated vesicle protein C; huntingtin-interacting protein 9; alpha-adaptin C; Huntingtin interacting protein J; clathrin assembly protein complex 2 alpha-C large chain; plasma membrane adaptor HA2/AP2 adaptin alpha C subunit; clathrin-associated/assembly/adaptor protein, large, alpha 2; ADTAB; HIP-9; CLAPA2; FLJ37177;
Gene ID	161
Uni Prot ID	O94973
m RNA Refseq	BC006155
Chromosome Location	11p15.5
Pathway	Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Endocytosis, organism-specific bios
MIM	607242

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