Human ADCY10 adenoviral particles

Name: Human ADCY10 adenoviral particles
SKU: AD00689Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00689Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00689Z
Description	Adenovirus with ORF of adenylate cyclase 10 (soluble) (ADCY10), transcript variant 1.
Gene	ADCY10
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	ADCY10 adenylate cyclase 10 (soluble) [ Homo sapiens ]
Gene Symbol	ADCY10
Synonyms	ADCY10; adenylate cyclase 10 (soluble); adenylate cyclase type 10; HCA2; Hypercalciuria; absorptive; 2; RP1 313L4.2; SAC; SACI; Sacy; soluble adenylyl cyclase; hsAC; AH-related protein; ATP pyrophosphate-lyase; 3,5-cyclic AMP synthetase; germ cell soluble adenylyl cyclase; testicular soluble adenylyl cyclase (SAC); RP1-313L4.2;
Gene ID	55811
Uni Prot ID	Q96PN6
m RNA Refseq	BC117366
Chromosome Location	1q24
Function	ATP binding; ATPase binding; adenylate cyclase activity; magnesium ion binding; manganese ion binding; nucleotide binding;
Pathway	Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
MIM	605205

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