Human ADCY1 adenoviral particles

Name: Human ADCY1 adenoviral particles
SKU: AD00688Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00688Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00688Z
Description	Adenovirus with ORF of adenylate cyclase 1 (brain) (ADCY1).
Gene	ADCY1
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	ADCY1 adenylate cyclase 1 (brain) [ Homo sapiens ]
Gene Symbol	ADCY1
Synonyms	AC1
Gene Description	adenylate cyclase 1 (brain)
Gene ID	107
Uni Prot ID	Q08828
m RNA Refseq	NM_021116.2
Protein Refseq	NP_066939.1
Chromosome Location	7p13-p12
Function	ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; metal ion binding;
Pathway	Activation of GABAB receptors, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adenylate cyclase activating pathway, organism-specific biosystem; Adenylate cyclase inhibitory pathway, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Aquaporin-mediated transport, organism-specific biosystem;
MIM	103072

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