Human ADAM12 HEK293 Cell Lysate

Name: Human ADAM12 HEK293 Cell Lysate
SKU: CLOE-1121
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1121 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1121
Introduction	This cell lysate over-expresses the extracellular domain of the human ADAM12 (NP_003465.3) (Met 1-Ser 513) fused with a polyhistidine tag at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ADAM12
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ]
Gene Symbol	ADAM12
Synonyms	MCMP; MLTN; MLTNA; MCMPMltna
GeneID	8038
Uni ProtID	O43184
mRNA Refseq	NM_003474.4
Protein Refseq	NP_003465.3
Chromosome Location	10q26.3
Function	SH3 domain binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding;
Pathway	Disease, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by EGFR, organism-specific biosystem; Signaling by EGFR in Cancer, organism-specific biosystem; Syndecan-4-mediated signaling events, organism-specific biosystem;
MIM	602714

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