GSS Knockout Cell Line-293T

Name: GSS Knockout Cell Line-293T
SKU: CSC-RT0406

For research use only. Not intended for any clinical use.

Cat.No.

CSC-RT0406

Description

293T-GSS (-/-) is a stable cell line with a homozygous knockout of human GSS

Background

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]

Host Cell

293T

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