FABP1 adenovirus

Fatty acid binding protein 1 (FABP1), also known as liver-type fatty acid binding protein (L-FABP), is an important intracellular carrier protein primarily expressed in the liver and small intestine. FABP1 plays a key role in lipid metabolism by facilitating the absorption, transport, and intracellular trafficking of long-chain fatty acids and other hydrophobic ligands, such as bile acids and eicosanoic acid. Due to its involvement in lipid homeostasis, FABP1 has been extensively studied in metabolic disorders, including non-alcoholic fatty liver disease (NAFLD), obesity, and diabetes. Furthermore, FABP1 is involved in cellular processes such as inflammation, oxidative stress, and cell proliferation, making it a potential therapeutic target for various liver-related diseases.

The FABP1 adenovirus is a recombinant viral vector designed to deliver the FABP1 gene to target cells, enabling efficient overexpression of the FABP1 gene for functional studies. Adenoviral vectors are widely used in gene therapy and research due to their high transduction efficiency, broad tropism, and ability to infect both dividing and non-dividing cells. The FABP1 adenovirus is particularly important for studying the role of this gene in lipid metabolism, liver function, and disease progression. Researchers use this tool to modulate FABP1 expression in hepatocytes or other relevant cell types, enabling analysis of its biological effects both in vitro and in vivo.