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Cat.No. : CSC-RT0105
Host Cell: HepG2 Target Gene: AHR
Size: 1x10^6 cells/vial, 1mL Validation: Sequencing
| Cat. No. | CSC-RT0105 |
| Description | HepG2-AhR cell line is a stable cell line with a homozygous knockout of AhR |
| Target Gene | AHR |
| Host Cell | HepG2 |
| Host Cell Species | Homo sapiens (Human) |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
A: The knockout cell product is validated by PCR amplification and Sanger Sequencing to confirm the mutation at the genomic level. Please find the detailed mutation info in the datasheet.
A: Single clonal cell.
A: No. This knockout cell product is generated using the CRISPR/Cas9 system to induce small insertions or deletions (indels) resulting in frameshift mutations. Although these frameshift mutations typically disrupt the coding gene, there is a possibility that the non-functional transcript may still be transcribed. Consequently, this could potentially yield misleading results when analyzed by RT-qPCR.
A: The cell line should be stored in liquid nitrogen for long-term preservation.
A: For most cases, we often keep at least 2 clones with different frameshift mutations. Please feel free to contact us to check if there are additional available clones.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
AhR Knockout Cell Line-HepG2 has truly been a highly competent helper in my research journey. Its exceptional knockout efficiency and consistent results have empowered me to uncover the hidden secrets of gene function with precision and confidence.
France
08/15/2021
I am completely impressed with the performance of AhR Knockout Cell Line-HepG2. Its reliable and reproducible knockout outcomes have provided me with a solid foundation for studying the role of specific genes in complex biological processes.
United States
10/09/2021
Using AhR Knockout Cell Line-HepG2 has been a seamless experience. Its intuitive interface and exceptional knockout efficiency have simplified the gene editing workflow, allowing me to focus more on data analysis and interpretation.
United States
01/27/2022
I cannot overstate the significance of AhR Knockout Cell Line-HepG2 in accelerating my research progress. Its high knockout success rate and consistent performance have propelled my investigations and facilitated groundbreaking discoveries.
United States
07/19/2022
I wholeheartedly recommend AhR Knockout Cell Line-HepG2 to my colleagues and fellow researchers. Its outstanding performance, ease of use, and reliable knockout results have revolutionized the way I study gene function, opening up new avenues of exploration.
United States
11/03/2022
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