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shRNA set against Rat EIF2S1 (NM_019356.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH284377

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Gene Information

Cat. No. SHH284377
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr EIF2S1
Gene Name Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha [ Mus musculus ]
Gene Symbol Eif2s1
Synonyms 35kDa; Eif2a; eIF2alpha; 0910001O23Rik; 2410026C18Rik
Gene Description eukaryotic translation initiation factor 2, subunit 1 alpha
Gene ID 13665
Uni Prot ID Q6ZWX6
m RNA Refseq NM_026114.3
Protein Refseq NP_080390.1
Chromosome Location 12; 12 D1
Function RNA binding; ribosome binding; translation initiation factor activity;
Pathway Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem;
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