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shRNA set against Rat CREB1 (NM_031017.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH269293

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Gene Information

Cat. No. SHH269293
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CREB1
Gene Name Creb1 cAMP responsive element binding protein 1 [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Creb1 cAMP responsive element binding protein 1 [ Mus musculus ]
Gene Symbol Creb1
Synonyms Creb; Creb-1; AV083133; 2310001E10Rik; 3526402H21Rik
Gene Description cAMP responsive element binding protein 1
Gene ID 12912
Uni Prot ID Q01147
m RNA Refseq NM_133828.2
Protein Refseq NP_598589.2
Chromosome Location 1 C2; 1 31.0 cM
Function DNA binding; RNA polymerase II activating transcription factor binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; cAMP response element binding; double-stranded DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription factor binding;
Pathway AKT phosphorylates targets in the nucleus, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem;
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