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shRNA set against Mouse Smad1 (NM_008539.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH412952

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Gene Information

Cat. No. SHH412952
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr Smad1
Gene Name Smad1 SMAD family member 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Smad1 SMAD family member 1 [ Mus musculus ]
Gene Symbol Smad1
Synonyms Mlp1; Madh1; Madr1; MusMLP; AI528653
Gene Description MAD homolog 1 (Drosophila)
Gene ID 17125
Uni Prot ID P70340
m RNA Refseq NM_008539.3
Protein Refseq NP_032565.2
Chromosome Location 8 C2; 8
Function I-SMAD binding; RNA polymerase II core promoter sequence-specific DNA binding; co-SMAD binding; identical protein binding; protein binding; protein kinase binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity;
Pathway Delta-Notch Signaling Pathway, organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Heart Development, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; PluriNetWork, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem;
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